The Surviving Sepsis Campaign Bundle: 2018 update

The Surviving Sepsis Campaign Bundle: 2018 update INTENSIVE CARE MEDICINE The Surviving Sepsis Campaign (SSC) has released a new updated Hour-1 Bundle to reflect the latest evidence from the International Guidelines for Management of Sepsis and Septic Shock 2016. In this revision of the SSC bundles, the 3-hour and 6-hour bundles have been combined into a single “Hour-1 Bundle” […]

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Impact of real-time TDM on the prescription of antibiotics in burn patients

EJRC Article Review Patients with burn injuries may experience marked pharmacokinetic (PK) changes compared to healthy volunteers and patients admitted without burn injuries. These PK changes are related to both specific pathophysiologic alterations and the frequent use of supportive therapy in burn injury patients. Therefore, achieving adequate antibiotic drug concentrations in burn patients is challenging1. […]

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What is the real impact of no sedation during mechanical ventilation?

What is the real impact of no sedation during mechanical ventilation? EJRC ARTICLE REVIEW   For many years, standard therapy for patients undergoing mechanical ventilation included sedation. It was seen as a way to ease patients and help them to accept the procedure. In the last decade, randomised controlled trials (RCTs) have shown that utilising […]

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ICUs in 2050: What end-of-life communication challenges await us?

ICUs in 2050: What end-of-life communication challenges await us? EJRC ARTICLE REVIEW   A paper in the “Intensive care medicine in 2050” article series published in recent months in Intensive Care Medicine, highlights how social and technological evolutions may have an impact on our way of communicating on end of life issues in the future […]

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