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Research – Trials

The aim of this project is to perform an international multicentre prospective observational cohort study of nosocomial pneumonia in intensive care units (ICUs) worldwide in order to provide up-to-date and comprehensive descriptive data on the diagnosis, microbiology, time course of resolution, management and outcomes in a global ICU population.

Secondary objective: Evaluate nosocomial pneumonia in specific subgroups of critically ill patients (such as, chronic obstructive pulmonary disease [COPD], the elderly, and trauma patients).

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Monitoring Organ Donors to Improve Transplantation Results. Will protocol guided resuscitation of brain dead organ donors using Pulse Pressure Variation (PPV) increase the number of organs transplanted per donor?

Publications:

Monitoring Organ Donors to Improve Transplantation Results (MOnIToR) trial methodology
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Protocolized fluid therapy in brain-dead donors: the multicenter randomized MOnIToR trial
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Role of Active Deresuscitation After Resuscitation (RADAR). Deresuscitation:minimisation of fluid administration, together with diuretics and perhaps ultrafiltration.

This survey aimed to characterise current beliefs and practice with regard to deresuscitation, the use of diuretics and/or renal replacement therapy to remove accumulated fluid in stable critically ill patients.
Preliminary resutls: Characterisation of fluid balance over time: preliminary results from the Role of Active Deresuscitation After Resuscitation (RADAR) study.

Research – Surveys

European Traumatic Shock Survey aimed to describe current critical care practices in the initial management of patients with traumatic haemorrhagic shock in Europe and compare these practices with contemporary guidelines.

Publication:

European trauma guideline compliance assessment: the ETRAUSS study

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Initial fluid management and use of vasopressors in adult severely burned patients: An European survey

This international survey focuses on the current practices in fluid management and the use of vasopressors for adult severely burned patients.

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Relevant research

Karim Asehnoune et al. The research agenda for trauma critical care.
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Jerry P. Nolan et al. Intensive care medicine research agenda on cardiac arrest.
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Post-admission outcomes of participants in the PARAMEDIC trial: A cluster randomised trial of mechanical or manual chest compressions.
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European Resuscitation Council and European Society of Intensive Care Medicine 2015 guidelines for post-resuscitation care
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The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition
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Article Reviews

Therapeutic Hypothermia: Survival After In-Hospital Cardiac Arrest
> Read the article review

Which resuscitation strategies have the best impact on patient outcome with in-hospital cardiac arrest?
> Read this article review

Delayed awakening after cardiac arrest
> Read this article review

Critically ill burn patients: How do we prevent, diagnose and treat complications? 
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Nurses versus physician-led interhospital critical care transport
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Rapid response teams implementation to reduce hospital mortality
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Chest Compression during CPR: Do ventilation interruptions really affect outcome?
> Read this article review

Ebola Resources

Ebola Virus Disease (EVD), also known as Ebola haemorrhagic fever, is a severe illness with a high mortality rate, particularly in affected patients who are untreated or have delayed treatment.  Ebola is transmitted by direct contact with blood, body fluids and tissues of infected animals or people and has an incubation period of 2 – 21 days.

ESICM & Ebola

The European Society of Intensive Care Medicine continues to closely monitor the 2014/15 Ebola outbreak and has prepared several initiatives and resources to help intensive care and emergency workers to prepare for and manage EVD. ESICM collaborated on this survey: Preparedness for admission of patients with suspected Ebola virus disease in European hospitals: a survey, August-September 2014 (12/2014). For more information on PREPARE – Platform foR European Preparedness Against (Re) emerging Epidemics  research centring on EVD, visit the website.

ESICM suggests the following links as a starting point for information on Ebola:

Europe:

VHF – Ebola Registry

There are indications that patients suffering from Ebola in western countries have a lower mortality rate, but since we currently lack information on the evolution of Ebola outside of Africa, we do not know what occurs when Ebola patients become dependent on organ support.

In order to better characterise these severe forms of the virus, the ESICM Trials Group have set up a VHF – Ebola Registry. Our aim is to better understand the most useful treatments and potential futility frontiers within this difficult disease. Centres who have data on patients who have been diagnosed with Ebola and treated in their ICU are welcome to register through the link here. If data collected in this registry is published, all contributors will be listed in the publication.

For further information, please contact: ebola@esicm.org

National Information & Resources

National Societies and representatives have provided specific contact information for their individual countries, which is available here.

Related Articles

Intensive Care Medicine journal has also published updated articles on diagnosis and treatment of Ebola. These articles can be freely accessed below.

Related Article Review: Ebola: What every intensive care health worker should know…

Videos 

EBOLA: A PERSONAL EXPERIENCE
icTV Interview with Mitchell Levy


Mitchell Levy sits down with icTV to share his experience, as a clinician – and a father faced with the unimaginable dilemma of dealing with having his son stricken with the ebola virus disease during the 2014 ebola outbreak in Western Africa.

Suggested talks

The PaRAMeDIC Trial

In this icTV interview, Gavin Perkins describes the rationale for the use of mechanical chest compression devices, and his recent trial on the clinical relevance and cost-effectiveness of the use of these devices out-of-hospital settings: The PaRAMeDIC Trial.

Results from this trial were presented during one of the clinical trial sessions at LIVES 2014 in Barcelona.

Publications:

Prehospital randomised assessment of a mechanical compression device in cardiac arrest (PaRAMeDIC) trial protocol
Post-admission outcomes of participants in the PARAMEDIC trial: A cluster randomised trial of mechanical or manual chest

Visit our e-LIVES platform to see more…

bouton-e-lives

The aftermath of the bombings

In this icTV video, Dr Serge Jennes, Head of the Burn Unit at Queen Astrid Military Hospital in Brussels, Belgium reflects on his experiences one year on from March 22, 2016 – the day of the Bombings in his home city. His hospital was one of the central hospitals to receive and treat the majority of the victims from the airport and metro attacks.
Dr Jennes describes his initial emotional reaction at learning of a mass casualty incident so close to home and the need to rely on his military experiences from Afghanistan in the clinical management of these trauma patients.

Where do we stand when it comes to transfusions?

In this icTV interview, Jean-Louis Vincent shares his thoughts on transfusion use in ICU patients, recent RCTs and which strategies should be adopted now and moving into the future.

Education

Webinar ~Targeted Temperature Management after Cardiac Arrest

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Webinar ~ Post-cardiac arrest management”

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