PARTICIPATE IN OUR OPEN TRIALS
The ESICM Trials Group has major trials which are either currently or soon to open for interested centres. Learn more about TRAIN, VITDALIZE, PrevAKI, DecubICUs and WEAN SAFE and register your interest in getting your ICU involved in these important clinical research initiatives in intensive care medicine! See all of the dedicated webpages for more information.
ESICM has supported several other long-term studies in recent years.
GenOSept: Genetics of Sepsis in Europe
It is hypothesised that the fatal outcome following treatment for severe sepsis is, in part, genetically determined. This hypothesis is based on preliminary data developed by several groups from studies of small, relatively homogeneous populations. GenOSept will test this hypothesis through three phases:
- A genetic epidemiologic study of genetic predisposition to sepsis-related mortality and morbidity in European intensive care units;
- This unique European dataset on the effect of genetic variation on sepsis outcomes will help to explain variation in response to new treatments for sepsis, will deliver data on gender related mortality and morbidity;
- Harmonisation of standards for European high throughput genotyping and quality control by co-ordinating three major European genotyping centres (Wellcome Trust Centre for Human Genetics – Oxford, Cochin Institute – Paris, Helmholtz Zentrum Munchen – Munich).
This project was supported by ESICM.