COVID-19

coronavirus is one of many viruses that cause diseases in mammals and birds. In humans, coronaviruses cause respiratory tract infections that are typically mild, such as the common cold, though rarer forms such as SARS, MERS and COVID-19 can be lethal.

A novel coronavirus (nCoV) is a new strain that has not been previously identified in humans.

Common signs of infection include respiratory symptoms, fever, cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death.

At the end of 2019, a novel Coronavirus (2019-nCoV) was found to be responsible for a cluster of atypical cases of pneumonia in Wuhan, China. Since then, the virus has spread both inside and outside China, and the WHO has declared this a public health emergency.

With the outbreak now present in Europe, and likely to affect many more areas over the coming months, we at ESICM have decided to help ICU professionals around the world by providing information that may make a vital contribution in the battle to contain the infection, treat the patients and to protect the frontline workers.

Learning from experience can save lives and, for this purpose, we are using this webpage to share key online resources, including manuscripts and summaries of papers published in the ICM journal and other important medical journals, podcast interviews with experts and colleagues who will discuss management strategies in place for preparedness and their own experiences on the ground.

ESICM will continue to provide the most up to date and crucial information in order to play its part and to face this global challenge.

GUIDELINES

Summary by David Lynes
Anaesthesia & Intensive Care, ESICM Editorial & Publishing Committee

Infographic by Marta Velia Antonini
CCN/CCP, MS Ist ICU University Hospital of Parma, Italy

FREE EDUCATIONAL CONTENT – ESICM ACADEMY

Acute Respiratory Distress Syndrome (ARDS)
> Access ACE- Course
> Download PDF

Acute respiratory failure ECLS
> Access ACE- Course
> Download PDF

Mechanical Ventilation
> Access ACE- Course
> Download PDF

INTERVIEWS

WEBINARS

First-hand experience of the situation in China

Wednesday 26 February

This recording gives first-hand experience and insight into the cases of the Coronavirus in Mainland China and how Northern Italy is responding to the situation it now faces.

Managing critically ill patients with the virus

Monday 9 March from 16.00-17.00 hrs CET

For this webinar, Prof. Yaseen ARABI and Dr. Lennie DERDE, two experts in respiratory syndrome, infectious threats and the treatment of severe infections presented the latest information on COVID-19.

National Coordination & Experience in Italy

Thursday 19 March from 16.00-17.00 hrs CET

For this third webinar, Prof. Antonio PESENTI and Prof. Massimo ANTONELLI,  two experienced scientists, will present latest data and discuss the national strategy in Italy for dealing with COVID-19.

ARTICLES

Articles published online on Intensive Care Medicine website (Springer) – free online

Review

Critical care management of adults with community-acquired severe respiratory viral infection.
Yaseen M. Arabi, Robert Fowler, Frederick G. Hayden in Intensive Care Medicine (2020).

Editorial

How to face the novel coronavirus infection during the 2019–2020 epidemic: the experience of Sichuan Provincial People’s Hospital.
Lingai Pan, Li Wang, Xiaobo Huang in Intensive Care Medicine (2020).

What’s New in Intensive Care

Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists.
Bouadma, L., Lescure, F., Lucet, J. et al. in Intensive Care Med (2020).

What’s New in Intensive Care

Novel coronavirus infection during the 2019–2020 epidemic: preparing intensive care units—the experience in Sichuan Province, China.
Xuelian Liao, Bo Wang, Yan Kang in Intensive Care Medicine (2020)

Letter

Challenges and countermeasures for organ donation during the SARS-CoV-2 epidemic: the experience of Sichuan Provincial People’s Hospital.
Lingai Pan, Jie Zeng & Hongji Yang. in Intensive Care Med (2020).

Letter

Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China.
Qiurong Ruan, Kun Yang, Wenxia Wang, Lingyu Jiang & Jianxin Song in Intensive Care Med (2020).

Letter

The novel coronavirus (SARS-CoV-2) infections in China: prevention, control and challenges.
Sheng Zhang, Meng Yuan Diao, Liwei Duan, Zhaofen Lin & Dechang Chen in Intensive Care Medicine (2020)

What’s New in Intensive Care

Critical care crisis and some recommendations during the COVID-19 epidemic in China.
Jianfeng Xie, Zhaohui Tong, Xiangdong Guan, Bin Du, Haibo Qiu & Arthur S. Slutsky in Intensive Care Med (2020).

Imaging in Intensive Care Medicine

Imaging changes in severe COVID-19 pneumonia.
Wei Zhang in Intensive Care Med (2020).

Imaging in Intensive Care Medicine

Imaging changes of severe COVID-19 pneumonia in advanced stage.
Wei Zhang in Intensive Care Medicine (2020)

Letter

Findings of lung ultrasonography of novel corona virus pneumonia during the 2019–2020 epidemic.
Qian-Yi Peng, Xiao-Ting Wang, Li-Na Zhang in Intensive Care Medicine (2020)

Letter

How to balance acute myocardial infarction and COVID-19: the protocols from Sichuan Provincial People’s Hospital
Jie Zeng, Jianxin Huang & Lingai Pan in Intensive Care Med (2020).

Letter

Clinical Features and Short-term Outcomes of 18 Patients with Corona Virus Disease 2019 in Intensive Care Unit
Jianlei Cao, Xiaoyong Hu, Wenlin Cheng, Lei Yu, Wen-Jun Tu & Qiang Liu in Intensive Care Med (2020).

Understanding the Disease

Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
Haibo Zhang, Josef M. Penninger, Yimin Li, Nanshan Zhong & Arthur S. Slutsky in Intensive Care Med (2020).

Letter

Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis
Xiu-wu Pan, Da Xu, Hao Zhang, Wang Zhou, Lin-hui Wang & Xin-gang Cui in Intensive Care Med (2020).

Guidelines

Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19)
Waleed Alhazzani, Morten Hylander Møller, […]Andrew Rhodes in Intensive Care Med (2020).

Articles accepted in Intensive Care Medicine (un-edited)

COVID-19 pneumonia: different respiratory treatment for different phenotypes?

> Read the Article

 

Clinicolaboratory Study of 25 Fatal Cases of COVID-19 in Wuhan

> Read the Article

Further reading & links to external resources & websites

Highlighted research articles and additional commentary from Springer journals.

JAMA Network COVID-19 Collection including Q&A.

Recommended articles and evidence from the Cochrane Library Special Collection.

Content from the Blog written by Tommaso Scquizzato & Giovanni Landoni of the Department of Anaesthesia & Intensive Care, IRCCS San Raffaele Scientific Institute, Milan (Italy).

ECDC information

The response of Milan’s Emergency Medical System to the COVID-19 outbreak in Italy – The Lancet

Elsevier’s Novel Coronavirus Information Center

Critical Care Clinics Issue focused on disaster medicine including pandemics