The Feeding, Rehabilitation, Endocrinology & Metabolism section is led by Arthur van Zanten.

FREM News

Resources

EDUCATION

Nutrition in Critical Illness

Format: Virtual
Dates: 24-25 April, 2024

The Course on Nutrition in critical illness provides participants with an introductory overview of the field of nutrition and metabolic management in intensive care.

A high level of interaction is the core feature of this full day of learning. This will be guaranteed thanks to interactive lectures, case-based discussions, gamification and much more. We are excited to welcome you to our new event!

Free live webinars are available for members & non members on the ESICM Media Library.

RESEARCH

VITDALIZE

A multicentre, placebo-controlled double-blind phase III randomised clinical trial to examine the effect of high-dose vitamin D3 on 28-day mortality in adult critically ill patients with severe vitamin D deficiency

To date, only 7 interventions (e.g. non invasive ventilation, prone positioning…) have demonstrated a mortality benefit for ICU patients in multicentre trials. If proven to be beneficial, vitamin D treatment in critically ill patients could be immediately implemented worldwide.

> Read more

iSOFA

Intestinal-Specific Organ Function Assessment. To prospectively evaluate the value of gastrointestinal symptoms alone and in combination with Intra-Abdominal Pressure (IAP), and Acute Gastrointestinal Injury (AGI) grades

To determine whether biochemical markers (plasma and urine) of intestinal injury are of additional prognostic value compared to clinical gastro-intestinal symptoms and AGI grades.

Read More

Study

Prospective, observational, multicentre study of gastrointestinal dysfunction in critically-ill patients. Development of gastrointestinal failure score

Publication:

Gastrointestinal symptoms during the first week of intensive care are associated with poor outcome: a prospective multicentre study.

Read More

ICU Nutrition Day

The specific aim of this project is to assess nutritional therapy in ICUs on a specific date in order to detect correlations between nutritional therapies and outcome based on a large European sample.
https://www.nutritionday.org/

Publications:

NutritionDay in Nursing Homes – The Association of Nutritional Intake and Nutritional Interventions With 6-Month Mortality in Malnourished Residents.
> Read more

NutritionDay: 10 years of growth
> Read more

GLUCONTROL

Comparative effects of two glucose control regiments by insulin in ICU patients. This project, which is now over, aimed at defining whether a tight glucose control by insulin improved the vital outcome in a mixed population of critically-ill patients.

Publications:

A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study.
> Read more

Glucontrol, no control, or out of control?
> Read more

  • Rehabilitation (Zudin Puthucheary)
  • Education (Danielle Bear & Sjoerd Van Bree)
  • Micronutrients (Angelique de Man)
  • GI function (Annika Reintam Blaser)

Anyone who is interested to be part of a project group and work on the respective projects can contact the delegate of the group.

Reintam Blaser A. et al. Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine. Crit Care. 2020 May 15;24(1):224. doi: 10.1186/s13054-020-02889-4

Cederholm T. et al. GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community. J Cachexia Sarcopenia Muscle. 2019 Feb;10(1):207-217. doi: 10.1002/jcsm.12383

Singer P. et al. ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr. 2019 Feb;38(1):48-79. doi: 10.1016/j.clnu.2018.08.037

Arabi Y.M. et al. The intensive care medicine research agenda in nutrition and metabolism. Intensive Care Med. 2017 Sep;43(9):1239-1256. doi: 10.1007/s00134-017-4711-6

Arabi Y.M. et al. The intensive care medicine research agenda in nutrition and metabolism. Intensive Care Med. 2017 Sep;43(9):1239-1256. doi: 10.1007/s00134-017-4711-6

Annane D. et al. Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. Crit Care Med. 2017 Dec;45(12):2078-2088. doi: 10.1097/CCM.0000000000002737

Arabi Y.M. et al. A critical view on primary and secondary outcome measures in nutrition trials. Intensive Care Med. 2017 Dec;43(12):1875-1877. doi: 10.1007/s00134-017-4894-x

Bagate F. et al. Association between relative adrenal insufficiency and septic cardiomyopathy: a preliminary report. Intensive Care Med. 2017 Dec;43(12):1924-1926. doi: 10.1007/s00134-017-4901-2

Martucci G. et al. The effect of high-dose cholecalciferol on bioavailable vitamin D levels in critically ill patients: a post hoc analysis of the VITdAL-ICU trial. Intensive Care Med. 2017 Nov;43(11):1732-1734. doi: 10.1007/s00134-017-4846-5

Pantoprazole prophylaxis in ICU patients with high severity of disease
> Read this article review

IRON supplementation in ICU patients: The IRONMAN Trial
> Read this article review

Abnormal liver tests in ICU patients: What do they really signal?
> Read this article review

NICE-SUGAR: Glucose Control in Traumatic Brain Injury
> Read this article review

Nutrition in the acute phase of critical illness: Recent findings
> Read this article review