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Research – Trials

TRansfusion strategies in Acute brain INjured patients is a prospective multicentre randomised interventional study.

This trial will assess the impact of two different strategies to administer blood transfusions in a large cohort of critically ill patients with a primary brain injury.

 

> Update
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An international prospective observational StudY on iNtrAcranial PreSsurE (ICP) in intensive care (ICU). Uncertainties remain around ICP monitoring both in traumatic and non-traumatic brain injury, and variation in clinical practice of ICP monitoring exists between ICUs.

The objectives of the study are to explore ICP monitoring variation in practice in order to prioritise uncertainties in the clinical management of critical care patients with acute brain injury and support further collaborative hypotheses based prospective studies.

Register your ICU, here

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EURopean study on Encephalitis in intensive Care. This is a prospective observational multicentre study in European ICUs. All patients admitted to the ICU for probable or confirmed AE (2013 IDSA criteria) will be included.

The main aims of the project are to describe the epidemiology and outcomes of patients admitted to the ICU with all-cause acute (meningo-) encephalitis in European countries.

 

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Research – Surveys

Current Practices for Neurological Prognostication after Cardiac Arrest. The aim of this survey was to investigate the current practice and timing of neurological prognostication after cardiac arrest in European ICUs.

Publication:

Friberg H et al., Survey on current practices for neurological prognostication after cardiac arrest.

> Read more

SUMMA: SUrvey on Fever Monitoring and Management in Patients with Acute Brain Injury

Results soon

Relevant research

Nicolas Weisset al. Understanding haepatic encephalopathy.
> Read more

Ary Serpa Neto et al. Known and unknown potentially modifiable factors contributing to outcome in brain-injured patients who need mechanical ventilatory support. Discussion on ‘The BI-VILI project: a nationwide quality improvement project’.
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Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals.
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Article Reviews

TTM: Is 48 hours at 33ºC better than 24?
The current resuscitation guidelines recommend a target temperature of between 33-36°C for at least 24 hours
> Read this article review

Modifiable factors contributing to sepsis-associated encephalopathy?
Data on potentially modifiable contributing factors (severe hypoxia, systemic hypotension, metabolic disturbances, use of sedative agents, antibiotics and steroids) to SAE are scarce
> Read this article review

Decompressive Craniectomy for Traumatic Intracranial Hypertension?
> Read this article review

Mens sana in corpore sano: new guidelines on delirium, analgesia and sedation in the ICU
> Read this article review

Continuous Monitoring of Spinal Cord Pressure Possible after Spinal Cord Injury
> Read this article review

Is fever suppression beneficial or not?
> Read this article review

Do myoclonic jerks in post-cardiac arrest patients signal futility?
> Read this article review

Suggested talks

Neuromonitoring tips and tricks

KEYNOTE ~ NINO STOCCHETTI

Visit our e-LIVES platform to see more…

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EPO-TBI RESULTS

What effect does Erythropoetin have in TBI patients?
Craig French provides us with the results of his EPO-TBI trial in this icTV video. These results were presented for the first time during the HOT TOPICS session at LIVES 2015 and published simultaneously in The Lancet.

Visit our e-LIVES platform to see more…

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Visualising intracranial hypertension in adult and paediatric TBI

Geert Meyfroidt discusses results from a multicentre study aimed to assess the impact of the duration and intensity of episodes of increased intracranial pressure on 6-month neurological outcome in adult and paediatric TBI.

> Read this article in ICM’s June 2015 issue

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Education

Webinar ~ How do you manage ICP in severe traumatic brain injury?

> Watch Replay