Augmented renal clearance: Impact on continuously infused TZP concentrations?

Does augmented renal clearance have a negative impact on continuously infused TZP concentrations? EJRC Article Review Inappropriate antibiotic dosing has been linked to adverse infection outcomes1,2. Augmented renal clearance (ARC, >130mL/min) has been identified as a risk factor for low beta-lactam antibiotic concentrations in ICU patients 5,6. Because beta-lactam antibiotics have time-dependent killing properties, prolonging […]

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e-LIVES: October Highlights

e-LIVES: October Highlights Special interest sessions @LIVES 2018 This month we feature 6 top sessions which will be on offer at LIVES 2018 in Paris: Changing the paradigm: Personalised antibiotic dosing for the critically ill 22.10.2018 08:00-08:20 Presidents’ Ground Breaking Research Release 22.10.2018 16:00-18:11 ARDS phenotyping: A new era for clinical trials? 23.10.2018 08:00-08:20 Clinical […]

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Ventilator-associated complications in patients with ESBLE infections

Ventilator-associated complications in patients with ESBLE infections EJRC Article Review   Extended-spectrum b-lactamase producing Enterobacteriaceae (ESBLE) colonise a growing proportion of critically ill patients in the intensive care unit (ICU)[1]. ESBLE colonisation is an established risk factor for subsequent infections [2]. Although guidelines suggest to consider the colonisation status of patients to adjust empirical treatment […]

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Intensive Care Medicine: Access the latest ONLINE FIRST papers

ICM ONLINE FIRST THIS WEEK (FREE ACCESS) Review ~ Mohamed Abbas et al. Conflicts of interest in infection prevention and control research: no smoke without fire. A narrative review. From the Inside ~ Han Yan and Keegan Guidolin. Her ICU bed. Original ~ Lara Hessels et al. Urinary creatinine excretion is related to short-term and […]

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OBITUARY: Graham Ramsay

OBITUARY: Graham Ramsay We regret to announce the death of Professor Graham Ramsay, who died in hospital on September 7th 2018. He had been in deteriorating health for some years. Graham was President of ESICM from 2002 – 2004. His achievements included creating the PACT programme, and founding the Surviving Sepsis Campaign jointly with SCCM. […]

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