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PCT-guided antibiotic therapy in ICU patients

Procalcitonin-guided antibiotic therapy in intensive care unit patients: a systematic review and meta-analysis EJRC Article Review   Procalcitonin (PCT) is an acute-phase protein that has been extensively studied as a specific marker of bacterial infection. Its main proposed value is reduced use of antibiotics. PCT measurement has been recommended in the most recent edition of […]

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Reducing CRBSIs in ICUs: What’s the best strategy?

Reducing CRBSIs in ICUs: What’s the best strategy? EJRC Article Review   Background Healthcare-associated infections (HAIs) are associated with increased morbidity, mortality, and additional healthcare costs. Addressing modifiable factors including infection prevention and control (IPC) practices is a cost effective means of reducing the incidence of HAIs. The Prevention of Hospital Infections by Intervention and […]

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ICM THIS WEEK ~ ONLINE FIRST articles

ONLINE FIRST (FREE ACCESS) Letter ~ Béatrice La Combe et al. Decreased susceptibility to chlorhexidine affects a quarter of Escherichia coli isolates responsible for pneumonia in ICU patients. Letter ~ Fabio Silvio Taccone et al.  Estimated cerebral perfusion pressure among post-cardiac arrest survivors. Letter ~ François Vincent et al. Palliative cares and the intensivist: not confined to the […]

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Improving antibiotic stewardship in pneumonia: Is more aggressive viral testing the key?

Improving antibiotic stewardship in pneumonia: Is more aggressive viral testing a key to success? EJRC Article Review   Pneumonia has a substantial impact in the ICU, as a leading reason of acute respiratory failure and for mechanical ventilation. Since appropriate antibiotic use is crucial to limiting morbidity and mortality in pneumonia, intensivists normally prescribe broad-spectrum […]

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ICM ~ Your weekly ONLINE FIRST articles

ONLINE FIRST (FREE ACCESS)   Letter ~ François Stéphan et al. Outcome of unexplained acute respiratory distress syndrome with diffuse alveolar damage after lung transplantation. What’s New in Intensive Care ~ Irene Telias et al. The airway occlusion pressure (P0.1) to monitor respiratory drive during mechanical ventilation: increasing awareness of a not-so-new problem. Letter ~ Gérald Chanques et […]

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Are risk factors and impact of prevention strategies the same for early- and late-onset VAP?

Are risk factors and impact of prevention strategies the same for early- and late-onset VAP? EJRC Article Review   The risk factors and impact of prevention strategies for early-onset (EOP) versus late-onset (LOP) ventilator-associated pneumonia (VAP) are still under debate. Saied and colleagues conducted a retrospective analysis of data prospectively entered from 01/1997 to 03/2016 […]

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Do higher versus lower blood pressure targets reduce 28-day mortality in patients in shock?

icTV interview with François Lamontagne   In this icTV interview, François Lamontagne discusses the results of his patient‑data meta‑analysis of recent trials, which aimed to answer the research question: ‘In adult patients who are in shock, do higher versus lower blood pressure targets reduce 28-day mortality overall, or in subgroups defined by chronic hypertension, congestive […]

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