Augmented renal clearance: Impact on continuously infused TZP concentrations?

Does augmented renal clearance have a negative impact on continuously infused TZP concentrations? EJRC Article Review Inappropriate antibiotic dosing has been linked to adverse infection outcomes1,2. Augmented renal clearance (ARC, >130mL/min) has been identified as a risk factor for low beta-lactam antibiotic concentrations in ICU patients 5,6. Because beta-lactam antibiotics have time-dependent killing properties, prolonging […]

Read More…

e-LIVES: October Highlights

e-LIVES: October Highlights Special interest sessions @LIVES 2018 This month we feature 6 top sessions which will be on offer at LIVES 2018 in Paris: Changing the paradigm: Personalised antibiotic dosing for the critically ill 22.10.2018 08:00-08:20 Presidents’ Ground Breaking Research Release 22.10.2018 16:00-18:11 ARDS phenotyping: A new era for clinical trials? 23.10.2018 08:00-08:20 Clinical […]

Read More…

Ventilator-associated complications in patients with ESBLE infections

Ventilator-associated complications in patients with ESBLE infections EJRC Article Review   Extended-spectrum b-lactamase producing Enterobacteriaceae (ESBLE) colonise a growing proportion of critically ill patients in the intensive care unit (ICU)[1]. ESBLE colonisation is an established risk factor for subsequent infections [2]. Although guidelines suggest to consider the colonisation status of patients to adjust empirical treatment […]

Read More…

Intensive Care Medicine: Access the latest ONLINE FIRST papers

ICM ONLINE FIRST THIS WEEK (FREE ACCESS) Review ~ Mohamed Abbas et al. Conflicts of interest in infection prevention and control research: no smoke without fire. A narrative review. From the Inside ~ Han Yan and Keegan Guidolin. Her ICU bed. Original ~ Lara Hessels et al. Urinary creatinine excretion is related to short-term and […]

Read More…

e-LIVES: September webcast highlights

e-LIVES: September Highlights Top Acute Kidney Injury (AKI) Sessions   This month we feature 3 top sessions from LIVES 2017 in Vienna selected by Section Chair Eric Hoste: How will I prevent and treat AKI next year? Oliguria: What is the kidney telling us? An early start for RRT? This EXCLUSIVE CONTENT is available for all […]

Read More…

Guidance on the SSC Bundle

Guidance on the SSC Bundle NEW SSC animation video The Surviving Sepsis Campaign (SSC) Bundle is the core of the sepsis improvement efforts. Applying the sepsis bundle simplifies the complex processes of the care of patients with sepsis. The Surviving Sepsis Campaign Steering Committee and members of the Executive Committee collaborated to revise the bundle […]

Read More…