Is Trimodulin a safe and beneficial adjuvant therapy for adult patients with sCAP?

Is Trimodulin a safe and beneficial adjuvant therapy for adult patients with sCAP? EJRC Article Review Severe community-acquired pneumonia (sCAP) remains associated with high mortality despite widespread use of supportive care and targeted antibiotic therapy. Evidence suggests that IgM-enriched Immunoglobulin preparations are associated with a decrease in mortality in severe sepsis and septic shock. In […]

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Can cell surface markers predict risk of secondary infection?

The INFECT Study: Cell surface signatures of immune dysfunction risk stratify critically ill patients EJRC Article Review   Background In critically ill patients, immune activation is often accompanied by a state of immune depression. The persistence of this is associated with a complicated intensive care unit (ICU) course, including the development of nosocomial infections1. Objective […]

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Improving organ donation in ICU: What can make a difference?

Improving organ donation in ICU: What can make a difference?  ARTICLE REVIEW Organ donation, with its ability to improve quality of live and potentially save lives, has become a priority in many countries, and intensive care units are often play a central role in proposing potential donors. In spite of the different efforts focused on […]

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