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My ICU patient with acute hypoxaemic respiratory failure is immunocompromised

My ICU patient with acute hypoxaemic respiratory failure is immunocompromised: Results from the EFRAIM study EJRC Article Review   Over the past decades, the number of immunosuppressed patients admitted to ICUs has increased. This may be the consequence of increased use of chemotherapy, bone marrow and solid organ transplantation, as well as the increased life […]

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PCT-guided antibiotic therapy in ICU patients

Procalcitonin-guided antibiotic therapy in intensive care unit patients: a systematic review and meta-analysis EJRC Article Review   Procalcitonin (PCT) is an acute-phase protein that has been extensively studied as a specific marker of bacterial infection. Its main proposed value is reduced use of antibiotics. PCT measurement has been recommended in the most recent edition of […]

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Reducing CRBSIs in ICUs: What’s the best strategy?

Reducing CRBSIs in ICUs: What’s the best strategy? EJRC Article Review   Background Healthcare-associated infections (HAIs) are associated with increased morbidity, mortality, and additional healthcare costs. Addressing modifiable factors including infection prevention and control (IPC) practices is a cost effective means of reducing the incidence of HAIs. The Prevention of Hospital Infections by Intervention and […]

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Improving antibiotic stewardship in pneumonia: Is more aggressive viral testing the key?

Improving antibiotic stewardship in pneumonia: Is more aggressive viral testing a key to success? EJRC Article Review   Pneumonia has a substantial impact in the ICU, as a leading reason of acute respiratory failure and for mechanical ventilation. Since appropriate antibiotic use is crucial to limiting morbidity and mortality in pneumonia, intensivists normally prescribe broad-spectrum […]

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