How accurate are predictive outcomes for ventilator-associated events?

How accurate are predictive outcomes for ventilator-associated events? Results from the EUVAE study In 2013, the Centre for Disease Control and Prevention (CDC) proposed (and in 2015 updated) a new diagnostic algorithm for ventilator-associated events (VAEs) based on more objective criteria and easily measurable clinical features [1,2]. The algorithm divides the causes of respiratory worsening in […]

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The LIVES 2018 App: FREE TO DOWNLOAD NOW!

Download the LIVES 2018 App here: App Store Googleplay   This is your essential tool to fully connect to ESICM’s 31th Annual Congress LIVES 2018… GET CONNECTED NOW! […]

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Augmented renal clearance: Impact on continuously infused TZP concentrations?

Does augmented renal clearance have a negative impact on continuously infused TZP concentrations? EJRC Article Review Inappropriate antibiotic dosing has been linked to adverse infection outcomes1,2. Augmented renal clearance (ARC, >130mL/min) has been identified as a risk factor for low beta-lactam antibiotic concentrations in ICU patients 5,6. Because beta-lactam antibiotics have time-dependent killing properties, prolonging […]

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Ventilator-associated complications in patients with ESBLE infections

Ventilator-associated complications in patients with ESBLE infections EJRC Article Review   Extended-spectrum b-lactamase producing Enterobacteriaceae (ESBLE) colonise a growing proportion of critically ill patients in the intensive care unit (ICU)[1]. ESBLE colonisation is an established risk factor for subsequent infections [2]. Although guidelines suggest to consider the colonisation status of patients to adjust empirical treatment […]

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