Format: Virtual
February 22-23, 2024

This 2-day eCourse on Sepsis and Severe Infections provides important insights on the early recognition and diagnosis of severe infections and sepsis to prevent the transition into septic shock, which is associated with a mortality rate of 40%. Special attention is given to interactive activities, case-based discussions, workshops and problem-oriented approaches.

After registering for the event, ensure you access the dedicated online classroom on the ESICM Academy.

Hear from the experts

Course Directors

  • Liesbet DE BUS MD PhD, Department of Critical Care Medicine, Ghent University Hospital, Ghent, Belgium
  • Ricard FERRER MD, PhD, Head of Intensive Care Department / SODIR Research group-VHIR, University Hospital Vall d’Hebron; Associate Professor University of Barcelona, Barcelona, Spain; Past Chair of Systemic Inflammation and Sepsis (SIS) Section, ESICM
  • Pedro PÓVOA MD, PhD, Professor, NOVA Medical School, New University of Lisbon, Portugal; Adjunct Professor, Center for Clinical Epidemiology and Research Unit of Clinical Epidemiology, OUH Odense University Hospital, Denmark; Chair of CoBa faculty, European Society of Intensive Care Medicine; Section Editor of Intensive Care Medicine, Official Journal of ESICM; Associate Editor, RBTI, Official Journal of AMIB; Coordinator of the Intensive Care Unit 4, Dpt of Intensive Care, Hospital de São Francisco Xavier, CHLO, Lisbon, Portugal


  • Elsa AFONSO MSc, BSc (Hons), RN HEA Fellow Senior Faculty of Health, Education, Medicine and Social Care, Cambridge, United Kingdom
  • Massimo ANTONELLI MD Professor of Anesthesiology and Intensive Care Medicine, Università Cattolica del Sacro Cuore; Director of the Department of Anesthesiology and Intensive Care and Emergency Medicine, Fondazione Policlinico Universitario A.Gemelli IRCCS, Rome, Italy
  • Evelien DE JONG MD PhD Department of Critical Care, Rode Kruis Ziekenhuis Beverwijk | RKZ, Beverwijk, Netherlands
  • Jan DE WAELE MD PhD Professor, Dept. of Critical Care Medicine/ Surgical Intensive Care Unit, Ghent University Hospital, Belgium; Sr. Clinical Investigator – FWO – Research Foundation Flanders; Past-President, Belgian Society of Intensive Care Medicine; President elect, European Society of Intensive Care Medicine
  • Pieter DEPUYDT MD PhD Head of Clinic, Department of Intensive Care, Ghent University Hospital; Associate Professor, Department of Internal Medicine and Pediatrics, Ghent University, Belgium
  • Bruno FRANCOIS MD Department of Intensive Care medicine and Anaesthesiology, University Hospital of Limoges; Head of the Limoges Clinical Investigational Center, Limoges, France
  • Massimo GIRARDIS MD Department of Anaesthesiology and Intensive Care, University of Modena and Reggio Emilia and University Hospital of Modena, Lgo del Pozzo, Modena
  • Laura HAWRYLUCK MD Professor of Critical Care, University of Toronto; Physician Leader of CCRT at Toronto Western Hospital and Corporate Chair of University Health Network’s Acute Resuscitation Committee, Toronto, Canada
  • Isabel LEROUX-ROELS MD PhD Head of Department of CEVAC, Clinical microbiologist and infection control physician, Ghent University Hospital, Ghent, Belgium
  • Nathan D. NIELSEN MD M.Sc. FCCM Associate Professor, Division of Pulmonary, Critical Care and Sleep Medicine, University of New Mexico School of Medicine, Albuquerque, United States; Editorial Board and Sepsis Section Editor, ESICM Academy
  • Bryan O’FARRELL M Pharm MRPharmS – Clin Dip, IP, MSc. Critical Care Leads Pharmacist – Intensive Care & Theatres, Royal Free London NHS Foundation Trust, Royal Free Hospital, Pharmacy Dept, Pond Street, London, United Kingdom
  • Paula RAMIREZ MD, PhDHospital Universitario y Politécnico la Fe, Valencia, Spain

Endorsement:  The Course is endorsed by the Infection Section and the Systemic Inflammation and Sepsis Section, ESICM.

  • To review the current knowledge of the epidemiology and pathophysiology of infections and sepsis
  • To reinforce participants’ knowledge of recognition, source identification and initial treatment (antibiotics, organ support and fluid therapy)
  • To manage correctly the (frequent and less frequent) infections in the ICU setting
  • To employ the antibiotic stewardship: PKPD of antibiotics, biomarkers, duration and de-escalation of antibiotic therapy as well as preventive strategies
  • To diagnose and manage septic shock
  • To understand how to avoid, prepare and handle an outbreak of MDR/KPC
  • To understand the role of adjuvant therapies (safety, tolerability and impact)
  • Epidemiology
  • Diagnosis, Recognition and Source Identification
  • Initial Treatment and Bundles
  • Severe Infections (lung, abdominal, urinary tract)
  • Other infections (meningitis, endocarditis, skin infections)
  • Antibiotic Stewardship
  • How to implement ASP at the bedside
  • How to avoid, prepare and handle an outbreak of MDR/KPC in the ICU
  • Septic Shock
  • Adjuvant Therapies
  • Senior intensivists wanting a comprehensive review course
  • Intensive care trainees/residents seeking a training course on the integrated approach of a septic patient
  • Intensive care medicine and internal medicine MDs with a keen interest in sepsis and infections in the ICU
  • Researchers needing a better understanding of the clinical perspective of the management of sepsis and severe infections

IMPORTANT! A total of 10 places will be offered for FREE to participants coming from Low and Middle-Income Countries (LMIC), as per the World Bank classification. If you are interested to apply for an LMIC place, send us your letter of interest and CV to Applicants from LMIC may be selected for a maximum of 3 ESICM eCourses for FREE every year. Applicants who have participated in 1 eCourse as a free LMIC applicant need to have an active ESICM membership for the current year before applying again. 

Sepsis and Severe Infections, Virtual, Belgium 22/02/2024 – 23/02/2024 has been granted 12.0 European CME credits (ECMEC®s) by the European Accreditation Council for Continuing Medical Education (EACCME®).

Highlights of previous sessions


83 participants from 38 countries engaged in interactive activities and case-based discussions in this year’s edition. Here’s what they thought about the course experience: 

  • A really informative session.
  • So many take homes for our local application.
  • Lots of learning! Thank you!
  • Great learning experience, thanks to all faculty!
  • Thank you for an inspiring 2 days!


14 experts and 57 participants from 18 countries engaged in this highly interactive e-course with tailored sessions based on participants’ interests and the latest evidence in the field brought by our expert faculty. Check out their feedback below:

  • I think this was by far the most marvellous experience I’ve had with virtual education. Participation incentives and other fun activities were of paramount importance for a wholesome and intelligent learning experience.
  • It was definitely worth waking up for at 3:30 AM 😉
  • A brilliant Masterclass experience. I learned a lot. The platform was great.
  • Having such an experienced and world-renowned faculty in a breakout room to discuss face-to-face was just a privilege. Thanks to all of the respected faculty and technical team for making my experience spectacular.
  • Extremely refreshing and informative

2021 – September

Thanks to its incredible success, we held a second, virtual edition of the Sepsis and Severe Infections Master Class! A total of 9 experts and 80 participants from 31 countries engaged in this highly interactive course.

Here are some of the participants’ comments about their experience:

  • This Master Class was a great experience. Many thanks to the faculty for the effort and participants for sharing interesting thoughts
  • The sessions were very insightful. Many thanks to all the wonderful Faculty Members
  • My first time joining an ESICM MC indeed. Very fruitful learning experience. Big thanks to the Faculty and experts from around the world
  • Thank you very much, great masterclass to review concepts and to learn about new approaches
  • Very interesting and nice discussions to hear several views on the topic

2021 – February

Despite the uncertain context, we delivered another edition of the Sepsis and Severe Infections Master Class, this time virtually! A total of 9 experts and 78 participants from 32 countries engaged in interactive activities and case-based discussions.

Here are some of their comments on this innovative educational format:

  • The e-Master Class worked very nice for me. One can take most of the information from different experts and participants simultaneously
  • Absolute interactive and informative e-Master Class
  • It was my first ESICM Master Class but not the last one for sure. It was great!
  • Loved this format! It was way more interactive than I thought


We delivered another edition of the Sepsis and Severe Infections master class.  A total of 9 experts and 43 participants from 16 countries came together at the ESICM Training Centre in Brussels for this master class. Here are some of their comments on what they liked best about their experience:

  • International public, different international approaches; The small group discussions, and patient cases.
  • Excellent quality of lectures.
  • Open-minded and friendly approach and a great load of information. Despite the class having over 40 participants, everyone could participate and ask questions, there was a time for it in groups as well as in the whole class activities. On the other hand, the participants were not pushed to express themselves if they don’t want to. There was a great balance in this. I found the organisation amazing, the program went on time, but with a lot of breaks and moving which keep us awake (good point for me). The professors were high quality with a lot of knowledge, energy and open to discuss, supporting to ask the questions.
  • Discussion and interaction in small groups.


The second edition of the Sepsis and Severe Infections master class has just wrapped up. It came in continuation of two previous initiatives: Fundamentals & Updates in Sepsis and Managing Pneumonia in ICU. A total of 8 experts and 45 participants from 20 countries came together at the ESICM Training Centre in Brussels for this pilot master class. Here are some of their comments on what they liked best about their experience:

  • High-quality experts!
  • Meeting people from many other countries.
  • The possibility to formulate your own thoughts on therapy of sepsis and biomarkers
  • I found the infection-café’s extremely helpful. Well-led by the teachers, who had prepared the cases in advance. This way, I got a lot out of it.
  • The interactive nature of the event, the discussions and the friendliness and approachability of the experts.
  • The different ways the faculty tried to pass us information: pools, clinical cases, expert discussion
  • It was interactive and I enjoyed participating in all discussions.
  • Interaction during the case discussions; it should be stressed that the theoretical basis must be studied before (online) in order to get the most out of the course. In this way, the teachers may spend more time on case discussions.


The first edition of the Fundamentals & Updates in Sepsis Master Class was a resounding success! Participants from 10 countries came together for 2 days at the ESICM Training Centre in Brussels. Here are some of their comments on what they liked best about their experience:

  • Group discussions and case reports
  • Possibility to interact with experts
  • Being able to question the opinion leaders on this subject
  • The possibility of receiving lessons from European experts and meeting intensivists from all around Europe
  • The method to deliver high-level scientific presentations
  • The quality of the speakers and the attempt to make the event as interactive as possible

Social media: @ESICM #sepsis


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