Acute Kidney Injury

Intensive Care Nephrology Pathway
– Level 1: Foundation course in Intensive Care Nephrology
– Level 2: Transition course in Intensive Care Nephrology

Webinars

– Intensive Care Nephrology: building future progress on a legacy of success
– Precision medicine in Intensive Care Nephrology
– Lessons from Luciano Gattinoni: Physiological Insights Shaping the Future of Intensive Care
– Recent Developments in Intensive Care Nephrology
– Pathway in Intensive Care Nephrology – Kick off webinar

Podcasts

– Why does renal recovery from AKI matter to us intensivists?
– Sepsis-associated acute kidney injury in the intensive care unit

Free webinars and podcasts are available for members & non members on LIVES-STREAM.
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STARRT-AKI

Aim

To determine whether, in critically ill patients with severe acute kidney injury (AKI), a strategy of accelerated (early) initiation of renal replacement therapy (RRT), compared to a standard (delayed) strategy for initiation of RRT contributes to improved 90-day survival and recovery of kidney function.  

Design

Multi-national, multicentre, open-label, randomised, controlled trial. The trial is currently enrolling participants in 6 countries at 44 sites. The trial anticipates a total of 14 countries and approximately 100 sites.

AKI-EPI

Epidemiologic Prospective Investigation

The aim of the study is to evaluate the epidemiology and early management of acute kidney injury, according to the RIFLE classification in ICU patients.

Further information can be found at www.akinet.org.

Eric Hoste Interview

In this icTV interview, we sit down with Eric Hoste, to discuss the AKI-EPI study – one of the most accessed articles in Intensive Care Medicine in 2015/2016.

PrevAKI

PrevAKI is a multicentre, prospective, randomised controlled parallel group trial, which will assess biomarker-guided implementation of the KDIGO guidelines in the prevention of AKI. The pubication of the primary paper is expected  in the course of 2021.

The hypothesis: Implementation of the KDIGO guidelines in cardiac surgery patients at high risk for AKI identified by biomarker reduces the occurrence of AKI by approximately 15% compared to standard care.

– Global Landscape of Best Practices in Anticoagulation for CRRT: Lessons from the RCA survey (Global-RCA)
– FluidRRT
Publication: Murugan R et al. (2019) Net Ultrafiltration Prescription and Practice Among Critically Ill Patients Receiving Renal Replacement Therapy: A Multinational Survey of Critical Care Practitioners . Crit Care Med. 2019 Nov 13.

2025
Ostermann, M., Alshamsi, F., Artigas Raventos, A. et al. European Society of Intensive Care Medicine Clinical Practice Guideline on fluid therapy in adult critically ill patients: Part 3—fluid removal at de-escalation phase. Intensive Care Med (2025). https://doi.org/10.1007/s00134-025-08058-x

Ostermann, M., Forni, L.G., Joannidis, M. et al. State of the art: Renal recovery after AKI – from basic science to clinical practice. Intensive Care Med 51, 1490–1507 (2025). https://doi.org/10.1007/s00134-025-08035-4

Honore, P.M., Joseph, A. & Lee, H.Y. Kidney replacement therapy in critically ill obese patients: an urgent call for precision and evidence-based practice!. Intensive Care Med 51, 1522–1525 (2025). https://doi.org/10.1007/s00134-025-08028-3

Gaudry, S., Srisawat, N. & Joannidis, M. Renal replacement therapy. Intensive Care Med 51, 1514–1517 (2025). https://doi.org/10.1007/s00134-025-07987-x

Timing of Renal Replacement Therapy in Patients with Acute Kidney Injury and Sepsis

Effects of timing of renal replacement therapy in ICU patients with AKI

Can KDIGO panel guidelines prevent cardiac surgery-associated AKI?