Pharmacology and Pharmacotherapy

Core Skills in Intensive Care Pharmacotherapy 

• ACE course : Drug Dosing during Acute Kidney Injury and Renal Replacement Therapy | ESICM Academy
  Available on the ESICM Academy for the ESICM members

• WE: the ICU pharmacy professionals
• Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting

• AIRSPACE antimicrobial monographs: Jan de Waele, Cathrine A McKenzie and Professor Barbara Phillips
• Medication errors (collaboration with the NAHP and NEXT): Professor Richard Bourne
• GREEN ICU project: Dr Nicole Hunfield
• Intensive Care Fundamentals for pharmacists (collaboration with Professor Mo Al Haddad): Rhona Sloss

• Antimicrobial and pathogen surveillance in ICU (collaboration with INFECTION section): Professor Fredrik Sjoval

• McKenzie CA, Spriet I, and Hunfield N, Ten reasons for pharmacy professionals’ presence in the Intensive Care Unit. Intensive Care Medicine 2024. DOI: 10.1007/s00134-023-07285-4
• McKenzie CA, Srobik Y, Devlin J Less is more: Scheduled IV Opioids in Intensive Care, Intensive Care Medicine Accession Number: 37922011 DOI: 10.1007/s00134-023-07254-x
• Cheng, C., Walsh, A. A., Jones, S. S., Matthews, S. S., Weerasooriya, D. D., Fernandes, R. J., & McKenzie, C. A. (123456789). Development, implementation and evaluation of a seven-day clinical pharmacy service in a tertiary referral teaching hospital during surge-2 of the COVID-19 pandemic. International Journal of Clinical Pharmacy,https://doi.org/10.1007/s11096-022-01475-8
• Ankravs MJ, Mckenzie CA, Kenes MT. Precision‐based approaches to delirium in critical illness: A narrative review. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2023.DOI: 10.1002/phar.2807
• Shulman, R., McKenzie, C. A., Landa, J., Bourne, R. S., Jones, A., Borthwick, M., Tomlin, M., Jani, Y. H., West, D., Bates, (2015). Pharmacist’s review and outcomes: Treatment-enhancing contributions tallied, evaluated, and documented (PROTECTED-UK). Journal of Critical Care, 30(4)https://doi.org/10.1016/j.jcrc.2015.04.008
• Dulhunty JM, Brett SJ, De Waele JJ, et al. Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial. JAMA. 2024;332(8):629–637. Doi:10.1001/jama.2024.9779
• Chapuis C, Collomp R, Albaladejo L, Terrisse H, Honoré S, Bosson JL, Bedouch P, Albaladejo P. Redistribution of critical drugs in shortage during the first wave of COVID-19 in France: from operating theaters to intensive care units. J Pharm Policy Pract. 2022 Apr 1;15(1):28. Doi: 10.1186/s40545-022-00425-z.
• Chapuis C, Bedouch P, Detavernier M, Durand M, Francony G, Lavagne P, Foroni L, Albaladejo P, Allenet B, Payen JF. Automated drug dispensing systems in the intensive care unit: a financial analysis. Crit Care. 2015 Sep 9;19(1):318. doi: 10.1186/s13054-015-1041-3. PMID: 26349855; PMCID: PMC4563942.
• Chapuis C, Chanoine S, Colombet L, Calvino-Gunther S, Tournegros C, Terzi N, Bedouch P, Schwebel C. Interprofessional safety reporting and review of adverse events and medication errors in critical care. Ther Clin Risk Manag. 2019 Apr 2;15:549-556. Doi: 10.2147/TCRM.S188185. PMID: 31037029; PMCID: PMC6450184.
• Chapuis C, Roustit M, Bal G, Schwebel C, Pansu P, David-Tchouda S, Foroni L, Calop J, Timsit JF, Allenet B, Bosson JL, Bedouch P. Automated drug dispensing system reduces medication errors in an intensive care setting. Crit Care Med. 2010 Dec;38(12):2275-81. Doi: 10.1097/CCM.0b013e3181f8569b. PMID: 20838333.
• Chapuis C, Albaladejo P, Billon L, Catoire C, Chanoine S, Allenet B, Bouzat P, Bedouch P, Payen JF. Integrating a pharmacist into an anaesthesiology and critical care department: Is this worthwhile? Int J Clin Pharm. 2019 Dec;41(6):1491-1498. Doi: 10.1007/s11096-019-00909-0. Epub 2019 Oct 8. PMID: 31595449.
• Bourne RS, Jennings JK, Panagioti M, Hodkinson A, Sutton A, & Ashcroft DM. (2022). Medication-related interventions to improve medication safety and patient outcomes on transition from adult intensive care settings: a systematic review and meta-analysis. BMJ Quality & Safety, 31(8), 609–622.https://doi.org/10.1136/bmjqs-2021-013760
  https://qualitysafety.bmj.com/content/31/8/609
• Bourne RS, Herridge MS, & Burry LD. (2024). Less inappropriate medication: first steps in medication optimization to improve post-intensive care patient recovery. Intensive Care Medicine, 50(6), 982–985. Https://doi.org/10.1007/s00134-024-07405-8  
  https://link.springer.com/article/10.1007/s00134-024-07405-8