Feeding, Rehabilitation, Endocrinology & Metabolism

Nutrition in Critical Illness

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VITDALIZE

Intestinal-Specific Organ Function Assessment. To prospectively evaluate the value of gastrointestinal symptoms alone and in combination with Intra-Abdominal Pressure (IAP), and Acute Gastrointestinal Injury (AGI) grades

To determine whether biochemical markers (plasma and urine) of intestinal injury are of additional prognostic value compared to clinical gastro-intestinal symptoms and AGI grades.

iSOFA

WorldwidE AssessmeNt of Separation of pAtients From ventilatory assistancE is a multi-centre, prospective, observational, 4-week inception cohort study being carried out by the Acute Respiratory Failure section of ESICM. Weaning represents a challenge for intensivists and patients spend a considerable amount of time in being liberated from mechanical ventilation. While guidelines do exist on the classification of weaning, a recent study has shown that these may not be applicable to all patients.

Study

Prospective, observational, multicentre study of gastrointestinal dysfunction in critically-ill patients. Development of gastrointestinal failure score

Publication:

Gastrointestinal symptoms during the first week of intensive care are associated with poor outcome: a prospective multicentre study.

ICU Nutrition Day

The specific aim of this project is to assess nutritional therapy in ICUs on a specific date in order to detect correlations between nutritional therapies and outcome based on a large European sample.
https://www.nutritionday.org/

Publications:

NutritionDay in Nursing Homes – The Association of Nutritional Intake and Nutritional Interventions With 6-Month Mortality in Malnourished Residents.

NutritionDay: 10 years of growth

Glucontrol

Comparative effects of two glucose control regiments by insulin in ICU patients. This project, which is now over, aimed at defining whether a tight glucose control by insulin improved the vital outcome in a mixed population of critically-ill patients.

Publications:

A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study.

Glucontrol, no control, or out of control?

• Rehabilitation (Zudin Puthucheary)
• Education (Danielle Bear & Sjoerd Van Bree)
• Micronutrients (Angelique de Man)
• GI function (Annika Reintam Blaser)

Anyone who is interested to be part of a project group and work on the respective projects can contact the delegate of the group.

• Reintam Blaser A. et al. Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine. Crit Care. 2020 May 15;24(1):224. doi: 10.1186/s13054-020-02889-4
• Cederholm T. et al. GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community. J Cachexia Sarcopenia Muscle. 2019 Feb;10(1):207-217. doi: 10.1002/jcsm.12383
• Singer P. et al. ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr. 2019 Feb;38(1):48-79. doi: 10.1016/j.clnu.2018.08.037
• Arabi Y.M. et al. The intensive care medicine research agenda in nutrition and metabolism. Intensive Care Med. 2017 Sep;43(9):1239-1256. doi: 10.1007/s00134-017-4711-6
• Arabi Y.M. et al. The intensive care medicine research agenda in nutrition and metabolism. Intensive Care Med. 2017 Sep;43(9):1239-1256. doi: 10.1007/s00134-017-4711-6
• Annane D. et al. Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. Crit Care Med. 2017 Dec;45(12):2078-2088. doi: 10.1097/CCM.0000000000002737
• Arabi Y.M. et al. A critical view on primary and secondary outcome measures in nutrition trials. Intensive Care Med. 2017 Dec;43(12):1875-1877. doi: 10.1007/s00134-017-4894-x
• Bagate F. et al. Association between relative adrenal insufficiency and septic cardiomyopathy: a preliminary report. Intensive Care Med. 2017 Dec;43(12):1924-1926. doi: 10.1007/s00134-017-4901-2
• Martucci G. et al. The effect of high-dose cholecalciferol on bioavailable vitamin D levels in critically ill patients: a post hoc analysis of the VITdAL-ICU trial. Intensive Care Med. 2017 Nov;43(11):1732-1734. doi: 10.1007/s00134-017-4846-5

Pantoprazole prophylaxis in ICU patients with high severity of disease

IRON supplementation in ICU patients: The IRONMAN Trial

Abnormal liver tests in ICU patients: What do they really signal?

NICE-SUGAR: Glucose Control in Traumatic Brain Injury

Nutrition in the acute phase of critical illness: Recent findings