Sepsis in Immunosuppressed Patients: Pathophysiology, MDR Risk, and IgM-Enriched Therapy

Last updated : 24/04/2026 - 174 views

Sepsis in Immunosuppressed Patients: Pathophysiology, MDR Risk, and IgM-Enriched Therapy

Replay avaialble

Sepsis in immunosuppressed patients remains a major clinical challenge in intensive care. Altered immune responses, increased susceptibility to infection, and a higher risk of multidrug-resistant (MDR) pathogens make early recognition and targeted management particularly complex.

In this webinar, leading experts will explore the mechanisms driving sepsis in immunocompromised patients, discuss the growing impact of MDR infections, and examine the potential role of IgM-enriched immunoglobulin therapy as part of a tailored therapeutic approach.


Aims & Objectives

  • Understand the pathophysiological mechanisms of sepsis in immunosuppressed patients
  • Recognise the risk and clinical impact of multidrug-resistant infections in this population
  • Explore the potential role of IgM-enriched immunoglobulin therapy in sepsis management


Topics & Speakers 

Sepsis-induced immunosuppression: IgM kinetics and MDR vulnerability
Evangelos J. GIAMARELLOS-BOURBOULIS
Athens University School of Medicine, Athens (GR)

IgM-enriched immunoglobulins in sepsis: clinical evidence
Massimo GIRARDIS
University of Modena, Modena (IT)

MODERATOR

Marlies OSTERMANN 
Guy’s and St Thomas’​ NHS Foundation Trust, London (UK)

Thanks to the support of