LUNG SAFE Update
Upcoming publications & projects
LUNG SAFE (Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE) was the largest multicentre, prospective, observational study on hypoxaemic respiratory failure to be completed globally to date. This study, carried out by the Acute Respiratory Failure section through the ESICM Trials Group published its' primary paper in JAMA in February:
Bellani et al. Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA. February 23, 2016, Vol 315, No. 8.
Since then, the LUNG SAFE team has been working on the major pre-defined secondary analyses of the LUNG SAFE data. A second paper ‘Potentially modifiable factors contributing to outcome from Acute Respiratory Distress Syndrome: the LUNG SAFE study’ is in press in Intensive Care Medicine.
A third paper, which focuses on the impact of non-invasive ventilation, is in final revision with a major journal.
A fourth paper, which is examining the patient group with Acute Hypoxemic Respiratory Failure (non-ARDS) is in progress. A fifth paper, examining the geographic variations in ARDS demographics, management and outcome, is also well advanced.
There are also 17 OPEN LUNG SAFE projects which have been approved, so there are a number of interesting findings to come from this rich database. For more details and media links regarding this study as well as a full list of these upcoming projects, visit the LUNG SAFE webpage here.