May 11, 2017


In addition to our weekly ONLINE FIRST articles, please enjoy our newest ICM Pulse. This short video features results from the prospective, multicentre INSEP study into incidence of severe sepsis and septic shock amongst nearly 12,000 patients in 133 German intensive care units. This study demonstrates how the change from SIRS criteria to organ dysfunction in the new SEPSIS-3 definition of sepsis or septic shock may have a major impact on incidence and mortality rates.

Access this and all our ICM Pulse videos here.


Review ~ Alain Combes et al. The ICM research agenda on extracorporeal life support.

Original ~ Jean-François Timsit et al. Appropriate endpoints for evaluation of new antibiotic therapies for severe infections: a perspective from COMBACTE’s STAT-Net.

Original ~ Frank Bloos et al. Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomised trial.

Review ~ L. G. Forni et al. Renal recovery after acute kidney injury.

Original ~ Brennan C. Kahan et al. Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries

Editorial ~ Nicolas de Prost et al. Therapeutic targets in necrotising soft tissue infections.

What's New in Intensive Care ~ Demosthenes Makris et al. Ten ineffective interventions to prevent ventilator-associated pneumonia.

Editorial ~ Kevin B. Laupland and Ricard Ferrer. Is it time to implement door-to-needle time for “infection attacks”? 

Correspondence ~ Ary Serpa Neto et al. Known and unknown potentially modifiable factors contributing to outcome in brain-injured patients who need mechanical ventilatory support. Discussion on ‘The BI-VILI project: a nationwide quality improvement project’

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