Prophylactic melatonin for delirium in intensive care (Pro-MEDIC)

Last updated : 04/04/2022 - 29 views

Prophylactic melatonin for delirium in intensive care (Pro-MEDIC)

An ESICM Talk powered by the ICM Journal & the NEXT Committee

 

Delirium is a condition of acute organic brain dysfunction with fluctuating disturbances of attention and cognition, and its prevalence in intensive care units (ICUs) is recorded as high as 80%.

Delirium is highly distressing for patients and families and commonly reported as the worst experience of ICU admission. Melatonin has been described as an attractive intervention for delirium prevention, and a large study hypothesised that early administration of melatonin effectively reduces delirium in critically ill patients.

In this podcast, Dr Wibrow details the results of this study with Dr Scaramuzzo.