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Clinical and pathophysiological understanding of septic shock has progressed exponentially in the previous decades, translating into a steady decrease in septic shock-related morbidity and mortality.

Even though large randomised, controlled trials have addressed fundamental aspects of septic shock resuscitation, many questions still exist.

A comprehensive review was carried out to describe the current standards of septic shock resuscitation.

This review targeted the evolving concepts in different domains such as clinical resuscitation targets, adequate use of fluids and vasoactive drugs, refractory shock, and extracorporeal therapies.

To know more about the study, listen to Dr Hernandez and Dr Kattan, who were interviewed for this podcast by Dr Costa-Pinto.