Refractory Septic Shock: Definition (2026)
Join us on Tuesday, 29 September, 16:00 CEST
On World Heart Day, join us for an expert webinar exploring one of the most challenging forms of circulatory failure in critical illness: refractory septic shock.
What defines refractory septic shock in 2026? Why was a new definition needed, and how should we approach patients when standard resuscitation fails?
A timely discussion connecting sepsis, circulatory failure, and cardiovascular function, highlighting the importance of recognising and managing circulatory failure in critically ill patients.
Key Learning Objectives:
- Define refractory septic shock in 2026 and understand its clinical implications.
- Explore the management of refractory septic shock, including vasopressor strategies, adjunctive therapies and escalation.
- Understand the failing circulation, with a focus on macro- and microcirculatory dysfunction and monitoring.
Topics & Speakers
Defining refractory septic shock in 2026 — what has changed, why a new definition was needed, and its clinical implications
Flavia RIBEIRO MACHADO
Paulista School of Medicine, São Paulo (BR)
Managing refractory septic shock — vasopressor strategy, adjuncts, and escalation when standard resuscitation fails
Marc LEONE
Aix-Marseille University, Marseille (FR)
The failing circulation in refractory septic shock — macro- and micro-circulatory dysfunction and its monitoring
Daniel DE BACKER
Free University of Brussels, Brussels (BE)
MODERATORS
Antonio MESSINA
Humanitas University, Milan (IT)
Ahmed ZAHER
Oxford University Hospitals NHS Foundation Trust, Oxford (UK)