Acute kidney injury is common in critically ill patients, and 10-15% of ICU patients receive renal replacement therapy (RRT). The timing of therapy initiation is limited by heterogeneity, but until 10-15 years ago there was a trend toward early initiation, as noted by several meta-analyses.

In the past 5 years, several large PRCTs have addressed this topic: ELAIN, AKIKI, IDEAL-ICU, STARRT-AKI, and AKIKI-2 .

In this ESICM NEXT educational podcast, we will find out what is the most recent consensus and what are the clinical tools to facilitate the initiation of RRT.


Antoine SCHNEIDER. Lausanne University Hospital (CH). Chair, ESICM Acute Kidney Injury Section.

Ahmed ZAHER. Oxford University Hospitals (UK). ESICM Next Committee member.

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