PCT-guided antibiotic therapy in ICU patients

Procalcitonin-guided antibiotic therapy in intensive care unit patients: a systematic review and meta-analysis EJRC Article Review   Procalcitonin (PCT) is an acute-phase protein that has been extensively studied as a specific marker of bacterial infection. Its main proposed value is reduced use of antibiotics. PCT measurement has been recommended in the most recent edition of […]

Read More…

Improving antibiotic stewardship in pneumonia: Is more aggressive viral testing the key?

Improving antibiotic stewardship in pneumonia: Is more aggressive viral testing a key to success? EJRC Article Review   Pneumonia has a substantial impact in the ICU, as a leading reason of acute respiratory failure and for mechanical ventilation. Since appropriate antibiotic use is crucial to limiting morbidity and mortality in pneumonia, intensivists normally prescribe broad-spectrum […]

Read More…

Are risk factors and impact of prevention strategies the same for early- and late-onset VAP?

Are risk factors and impact of prevention strategies the same for early- and late-onset VAP? EJRC Article Review   The risk factors and impact of prevention strategies for early-onset (EOP) versus late-onset (LOP) ventilator-associated pneumonia (VAP) are still under debate. Saied and colleagues conducted a retrospective analysis of data prospectively entered from 01/1997 to 03/2016 […]

Read More…

Identifying community-acquired pneumonia (CAP)

Is the clinical significance of community-acquired pneumonia (CAP) visualised on CT scans only the same as of CAP visualised on chest x-rays? EJRC Article Review   The clinical significance of radiological signs of pneumonia visualised only on CT imaging is largely unknown, which creates uncertainty about the appropriate management: Should the management approach be according […]

Read More…