ARTICLE REVIEW
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Early vs. Standard Extubation in Hypoxemic Patients: a randomised clinical trial
Tag: extubation
Role of Lactate Kinetics over first 24 hours of ICU admission: a cohort study
Is Trimodulin a safe and beneficial adjuvant therapy for adult patients with sCAP?
Is Trimodulin a safe and beneficial adjuvant therapy for adult patients with sCAP? EJRC Article Review Severe community-acquired pneumonia (sCAP) remains associated with high mortality despite widespread use of supportive care and targeted antibiotic therapy. Evidence suggests that IgM-enriched Immunoglobulin preparations are associated with a decrease in mortality in severe sepsis and septic shock. In […]
What is the real impact of no sedation during mechanical ventilation?
What is the real impact of no sedation during mechanical ventilation? EJRC ARTICLE REVIEW For many years, standard therapy for patients undergoing mechanical ventilation included sedation. It was seen as a way to ease patients and help them to accept the procedure. In the last decade, randomised controlled trials (RCTs) have shown that utilising […]
My ICU patient with acute hypoxaemic respiratory failure is immunocompromised
My ICU patient with acute hypoxaemic respiratory failure is immunocompromised: Results from the EFRAIM study EJRC Article Review Over the past decades, the number of immunosuppressed patients admitted to ICUs has increased. This may be the consequence of increased use of chemotherapy, bone marrow and solid organ transplantation, as well as the increased life […]
Improving antibiotic stewardship in pneumonia: Is aggressive viral testing the key?
Improving antibiotic stewardship in pneumonia: Is more aggressive viral testing a key to success? EJRC Article Review Pneumonia has a substantial impact in the ICU, as a leading reason of acute respiratory failure and for mechanical ventilation. Since appropriate antibiotic use is crucial to limiting morbidity and mortality in pneumonia, intensivists normally prescribe broad-spectrum […]
Terminal weaning or immediate extubation: the ARREVE observational study
EJRC Article Review Terminal weaning or immediate extubation for withdrawing mechanical ventilation in critically ill patients (the ARREVE observational study) Worldwide, an increasing number of deaths occur in the intensive care unit (ICU) after a decision to withdraw life support [1, 2]. Relatives of patients who die in the ICU have been reported to experience […]
Identifying community-acquired pneumonia (CAP)
Is the clinical significance of community-acquired pneumonia (CAP) visualised on CT scans only the same as of CAP visualised on chest x-rays? EJRC Article Review The clinical significance of radiological signs of pneumonia visualised only on CT imaging is largely unknown, which creates uncertainty about the appropriate management: Should the management approach be according […]
Oxygen Therapy in AMI?
EJRC Article Review A new perspective for Oxygen Therapy in Suspected Acute Myocardial Infarction Traditional treatment for patients with suspected acute myocardial infarction (AMI) includes morphine, oxygen, nitroglycerine and aspirin. According to the European Society of Cardiology Guidelines for the management of AMI, oxygen is recommended in patients with ST-segment elevation in case of […]
ARDS: What is the optimal PEEP?
EJRC Article Review Effect of lung recruitment and titrated positive end-expiratory pressure (PEEP) vs. low PEEP on mortality in patients with ARDS Acute Respiratory Distress Syndrome (ARDS) is a clinical syndrome with various etiologies that usually occurs between 24 and 48 hours after local injury (pulmonary ARDS) or generalised acute illness (extrapulmonary ARDS). It […]
