What is the real impact of no sedation during mechanical ventilation?

What is the real impact of no sedation during mechanical ventilation? EJRC ARTICLE REVIEW   For many years, standard therapy for patients undergoing mechanical ventilation included sedation. It was seen as a way to ease patients and help them to accept the procedure. In the last decade, randomised controlled trials (RCTs) have shown that utilising […]

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Are SOFA, SIRS, PELOD-2, and qSOFA accurate outcome predictors in children?

EJRC Article Review   Paediatric sepsis definitions are based upon expert consensus from the International Paediatric Sepsis Consensus Conference [1]. The adult Sepsis-3 update on definitions has changed how patients with sepsis are identified, thus impacting on the research and quality indicators associated with its management [2]. Schlapbach et al. compared the performance of SIRS, […]

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Reviving glucocorticoids to treat Sepsis?

Reviving glucocorticoids to treat Sepsis? EJRC Article Review   Certainly, one of the greatest calamities of the modern world is Sepsis, which, despite the great advances in medicine, still doesn’t have a specific pharmacological treatment. This could be explained by the nature of Sepsis, as a very complex pathological entity, capable of affecting multiple organs, […]

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ICUs in 2050: What end-of-life communication challenges await us?

ICUs in 2050: What end-of-life communication challenges await us? EJRC ARTICLE REVIEW   A paper in the “Intensive care medicine in 2050” article series published in recent months in Intensive Care Medicine, highlights how social and technological evolutions may have an impact on our way of communicating on end of life issues in the future […]

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Pressure injuries and sedation: Are they related?

Pressure injuries and sedation: Are they related?  EJRC ARTICLE REVIEW Critically ill patients inherently have most of the risk factors for the development of pressure injuries. One of the key factors is immobility, which is very frequent in ICUs. This lack of mobility is enhanced by the administration of sedation and a decreased consciousness of […]

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My ICU patient with acute hypoxaemic respiratory failure is immunocompromised

My ICU patient with acute hypoxaemic respiratory failure is immunocompromised: Results from the EFRAIM study EJRC Article Review   Over the past decades, the number of immunosuppressed patients admitted to ICUs has increased. This may be the consequence of increased use of chemotherapy, bone marrow and solid organ transplantation, as well as the increased life […]

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PCT-guided antibiotic therapy in ICU patients

Procalcitonin-guided antibiotic therapy in intensive care unit patients: a systematic review and meta-analysis EJRC Article Review   Procalcitonin (PCT) is an acute-phase protein that has been extensively studied as a specific marker of bacterial infection. Its main proposed value is reduced use of antibiotics. PCT measurement has been recommended in the most recent edition of […]

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Reducing CRBSIs in ICUs: What’s the best strategy?

Reducing CRBSIs in ICUs: What’s the best strategy? EJRC Article Review   Background Healthcare-associated infections (HAIs) are associated with increased morbidity, mortality, and additional healthcare costs. Addressing modifiable factors including infection prevention and control (IPC) practices is a cost effective means of reducing the incidence of HAIs. The Prevention of Hospital Infections by Intervention and […]

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