Endorsed Research Projects
If you would like to know how ESICM endorsement works, please consult the rules.
To submit your project for endorsement or support, please use the project application form.
Do not hesitate to contact the office if you have any questions.
Procedures for ethical committees vary across countries. In order to facilitate the organisation of your trial you can find relevant information on the European Network of Research Ethics Committees website and on the WHO National Committees database.
Current Research Projects
SKin and soft tissue necrotizing INfections in the Intensive Care Unit: a prospective multi-national cohort study
PRone positioN in patients with spontanEous ventiLation and acute respIratory FailurE
The Outcome of Intoxicated patients in Europe-Toxic-Europe study
International Point Prevalence Study of Intensive Care Unit Transfusion Practices –InPUT study
Corona Virus Disease (COVID19) in Very Elderly Intensive care Patients
Multicenter ObserVational Study on PracticE of VeNTilation In Brain Injured PAtIeNts
INternational observational study To Understand the impact and BEst practices of airway management in critically ill patients (INTUBE)
SQUEEZE is a prospective multicentre international observational study of postoperative vasopressor usage
PRospective multicenter Observational study on Transfusion practice in vv-ECMO Patients: The PROTECMO Study
Extubation strategies in Neuro-ICU patients and associations with outcomes
Very old Intensive Care Patient-study 2: Development and validation of a prognostic score
International Study on NoSocomial Pneumonia in Intensive CaRE
EURopean study on Encephalitis in intensive Care.
Established Investigator Award winner 2017.
Weaning from mechanical ventilation: comparison of open-loop decision support system and routine care, in general medical ICU
STandard versus Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury
Completed Research projects
List of endorsed projects
• Practice Pattern Variation in Discontinuing Mechanical Ventilation in Critically-ill Adults: An International Prospective Observational Study
Lead Investigator: Karen E.A. Burns
• DALI – Defining Antibiotic Levels in Intensive care unit patients
Lead investigator: Jeffrey Lipman
• The use of MRI derived biomarkers to predict consciousness recovery in TBI, aSAH, ICH and HIE patients
Lead Investigator: Louis Puybasset
• AspICU2 – Invasive Fungal Disease in the ICU
Lead Investigator: Stijn Blot
• Prospective, randomised, multi-centre trial of lateral trendelenburg versus semi-recumbent body position in mechanically ventilated patients for the prevention of ventilator-associated pneumonia
Principal investigators: Gianluigi Li Bassi and Mauro Panigada
• EGUARD – Early e-guided use of antibiotics related to resistance data
Lead investigator: Claudia Spies
• CAPUCI II – Community Acquired Pneumonia in Europe
Lead Investigator: Jordi Rello
• MOnIToR – Monitoring Organ Donors to Improve Transplantation Results
Lead investigator: Rupert Pearse
• IMPROVE-ICU – International Multicentre one day Prevalence ObserVational study for dElirium on ICU
Lead investigator: Claudia Spies
• ELOISE – European mortality & Length Of ICU Stay Evaluation
Lead investigator: Maurizia Capuzzo
• EuSOS – European Surgical Outcomes Study
Lead investigator: Rupert Pearse
• INTERNATIONAL SURVEY ON FROZEN PLASMA TRANSFUSION PRACTICES
Lead investigator: Oliver Karam
• ReFIT – Resuscitation from Shock Using Functional Haemodynamic Monitoring
Lead Investigator: Michael R. Pinsky
• GENOSEPT – Genetics of Sepsis in Europe
Lead Investigator: Frank Stueber
• PROSPECTIVE, OBSERVATIONAL, MULTICENTRE STUDY OF GASTROINTESTINAL DYSFUNCTION IN CRITICALLY-ILL PATIENTS. DEVELOPMENT OF GASTROINTESTINAL FAILURE SCORE
Lead Investigator: Manu Malbrain
• H1N1 Flu – H1N1 Flu Registry on Intensive Care
Lead Investigator: Jordi Rello
• EURO-BACT– Epidemiology and outcome of Hospital-acquired bacteremia (HAB) in 2010
Jean-François Timsit for the Eurobact steering committee
• ICU NUTRITION DAY
Lead Investigator: Michael Hiesmayr
• IHPOTOTAM – Induced Hypothermia to treat Adult Meningitis
Lead Investigator: Bruno Mourvillier
• CoBaTrICE-IT – Competency-based Training in Intensive Care Medicine in Europe – Innovation Transfer
Lead Investigator: Julian Bion
• CoBaTrICE – Competency-based Training in Intensive Care Medicine in Europe
Lead Investigator: Julian Bion
• CORTICUS – Corticosteroid therapy of septic shock
Lead Investigator: Charlie Sprung
• ECRF
Lead Investigator: Julian Millo
• ELDICUS – Triage decision making for the elderly in European Intensive Care Units
Lead Investigator: Charlie Sprung
• IPOC – International Programme for Resource use in Critical Care
Lead Investigator: David Edbrooke
• PRICE – Physical Restraints in Intensive Care in Europe
Lead Investigator: Julie Benbenishty
• SAPS 3 – From the evaluation of the individual patient to the evaluation of the ICU
Lead Investigator: Rui Moreno
• SEE & SEE 2 – Sentinel Events Evaluation
Lead Investigator: Andreas Valentin
List of supported projects
• Sentinel Events Evaluation 3 (SEE 3), a Multinational observational study on safety of intrahospital transport in intensive care patients
Lead Investigator: Andreas Valentin, Institution: Rudolfstiftung Hospital, Vienna, Austria
• Monitoring resuscitation in severe sepsis and septic shock ‘MORESS‘, a prospective randomised multicentre study
Lead Investigator: Xaime García Nogales, Hospital de Sabadell, Barcelona, Spain.
• Cardiovascular Monitoring & Management in Austrian, German and Swiss Intensive Care Units – The ICU CardioMan Study
Lead Investigators: Daniel Reuter and Michael Sander
• DecoloniSation strategies in Intensive Care
• PROSAFE – Promoting patient safety and quality improvement in critical care
Lead investigator: Guido Bertolini
• ASP-ICU – Aspergillus in Intensive Care Units
Lead Investigator: Stijn Blot
• EVIDENCE – Evidence of Infection Prevention in Intensive Care Nurses’ Daily Practice
Lead Investigator: Stijn Blot
• SATURN – Impact of Specific Antibiotic Therapies on the prevalence of hUman host ResistaNt bacteria
Lead investigator: MJM Bonten
• CALOR 2003 – Severe heat stroke admitted to ICUs across Europe in August 2003: an observational survey
Lead Investigator: Djillali Annane
• EPIC II – European Prevalence of Infection in Intensive Care II
Lead Investigator: Jean-Louis Vincent
• AKI-EPI – Acute Kidney Injury – Epidemiologic Prospective Investigation
Lead Investigator: Eric Hoste
• ETHICATT – Systematic Study of General Ethical Principles Involved in End of Life Decisions for Patients in European Intensive Care Units
Lead Investigator: Charlie Sprung
• EU-VAP/CAP – Pneumonia in Patients requiring mechanical ventilation in European Intensive Care Units
Lead Investigator: Jordi Rello
• GAINS – Genomic Advances in Sepsis
Lead Investigator: Charles Hinds
• GLUCONTROL – Comparative effects of two glucose control regiments by insulin in ICU patients
Lead Investigator: Jean-Charles Preiser
• EUROBEDHEAD – European evidence-based consensus recommendation on bed head elevation policies for mechanically ventilated patients
Lead investigator: Barbara Niël-Weise
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