ESICM Regional Conference Athens 2017: Monitoring of shock

Getting the most out of arterial blood pressure monitoring (M Pinsky)

Arterial pressure waveform – Systolic, mean, diastolic and pulse pressure

Systolic AP (which changes depending on where you measure it)

  • LV SV
  • Ejection velocity (contractility)
  • Arterial elastance

Sepsis reverses the normal pulse pressure amplification down the arterial tree – therefore you would be underestimating the pressure in the aorta.

Diastolic pressure – determines coronary blood flow

  • vascular tone
  • arterial resistance
  • heart rate

Large arteries are capacitor

Faster heart rate means that the diastolic pressure hasn’t had time to stabilise – it may actually be much lower (vasodilatation). Increased HR is the main physiological response to vasodilation to maintain diastolic pressure.

Perfusion pressure = input – output pressure

Personalizing blood pressure management in septic shock

Pulse pressure influenced by

  • SV
  • Central arterial elastance
  • vascular stiffness, blood viscosity

The relationship between stroke volume and arterial pressure is determined by the elastance

Dynamic arterial elastance to predict arterial pressure response to volume loading in preload-dependent patients


Cardiac output monitoring: invasive or non-invasive? (T Scheeren)

Invasive monitors

  • Thermodilution (pulmonary thermodilution is considered the gold standard)
  • Pseudo randomised thermo signal (Vigilance)

Mini invasive



The Use of Pulmonary Artery Catheter in Sepsis Patients: A Literature Review

National Trends in Use and Outcomes of Pulmonary Artery Catheters Among Medicare Beneficiaries, 1999-2013

Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine

Perioperative cardiovascular monitoring of high-risk patients: a consensus of 12


Is CVP useful? PRO (S Magder)

Right Atrial Pressure in the Critically Ill: How to Measure, What Is the Value, What Are the Limitations?

CVP still the most used variable to guide fluid management in FENICE! 

CVP does not

  • indicate magnitude of blood volume
  • does not predict response to fluid

CVP normally low, elevated CVP needs explanation. CVP single value is not helpful.

The clinical role of central venous pressure measurements.

Systematic review including re-analyses of 1148 individual data sets of central venous pressure as a predictor of fluid responsiveness.

Where is your reference/zero point???

What point of the wave are you recording your value?

CVP is best used with some measure of flow. Fall in CO with fall in CVC = return function (volume) problem. Fall in CO but rise in CVC = primarily pump problem

Most useful in response to therapy.

Fluids after cardiac surgery: a pilot study of the use of colloids versus crystalloids.


Is CVP useful? CON (P Marik)

CVP is useless (mostly) and harmful (almost always)

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Iatrogenic salt water drowning and the hazards of a high central venous pressure


Does central venous pressure predict fluid responsiveness? A systematic review of the literature and the tale of seven mares.

CVP > 8 predicts AKI – Association between systemic hemodynamics and septic acute kidney injury in critically ill patients: a retrospective observational study

Impact of Initial Central Venous Pressure on Outcomes of Conservative versus Liberal Fluid Management in Acute Respiratory Distress Syndrome

Central venous pressure is a stopping rule, not a target of fluid resuscitation.