Category Archives: Respiratory

Adaptive research during pandemic – #ESICMtv #COVIDmarathon

Lennie Derde


Adaptive designs in clinical trials: why use them, and how to run and report them

The Platform Trial An Efficient Strategy for Evaluating Multiple Treatments

Fusing Randomized Trials With Big Data The Key to Self-learning Health Care Systems?

Adaptive platform trials: definition, design, conduct and reporting considerations

The Presentation

ESICM Webinar: How to ventilate in COVID-19

Luigi Camporota, UK

Watch the replay here: How to ventilate in COVID-19


My twitter thread on the webinar

The phenotypes of the disease and the time course

Remember, spontaneous breathing is not always a good thing…..

A stepwise approach to mechanical ventilation…

In conclusion…




And FOAMecmo’s beautiful infographic


Mechanical Ventilation – Basic to Advanced (Masterclass)


  • Controlled MV settings: basics
  • How to assess respiratory mechanics at the bedside
  • Strategies to set PEEP and to achieve lung recruitment

Revisiting the basics of mechanical ventilation with a nice quiz at the end…

Highly recommend   – great (free), short videos on mechanical ventilation


Recruitment Manoeuvres: 3 ways of doing it ….

  • sustained inflation
  • pressure controlled ventilation
  • incremental (decremental) PEEP trial

The ART trial highlighted the potential dangerous of recruitment manoeuvres. It’s effect may be dependant on determining which patients have recruitable lungs in the first place….

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@luigi_ICM  suggests that an assessment of potential lung recruitability MUST be performed prior to RM.


Do you know your respiratory mechanics equation??

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